Table 5. Changes in LCI and MMEF% predicted during exacerbation and post-antibiotic treatment visit.

	Parameter	Baseline levels	Bronchiectasis exacerbation		Post-antibiotic treatment visit
			Change from baseline Median (95% CI)	P value*	Change from exacerbation Median (95% CI)	P value**
All patients	No.	–	22	–	20	–
	LCI	16.65 (4.43)	0.38 (−2.34, 1.78)	0.50	−0.06 (−1.86, 0.72)	0.36
	MMEF predicted%	25.60 (30.05)	−2.00 (−8.23, 2.18)	0.28	−0.75 (−4.26, 3.69)	0.82
BSI <5	No.	–	7	–	6	–
	LCI	15.07 ± 2.63	0.39 (−1.68, 2.46)	0.66	−0.17 (−2.01, 1.66)	0.82
	MMEF predicted%	36.80 (22.50)	−0.16 (−10.62, 10.31)	0.97	4.72 (−5.35, 14.80)	0.28
5 ≤ BSI < 9	No.	–	6	–	5	–
	LCI	14.75 ± 3.11	−0.53 (−3.59, 2.53)	0.67	0.03 (−4.81, 4.86)	0.99
	MMEF predicted%	41.07 ± 22.17	4.09 (−4.82, 12.99)	0.29	−1.02 (−10.57, 8.53)	0.78
BSI ≥9	No.	–	9	–	9	–
	LCI	19.27 ± 6.30	0.04 (−5.53, 3.85)	0.68	0.20 (−3.42, 0.69)	.16
	MMEF predicted%	19.40 (36.20)	−2.40 (−15.45, 4.60)	0.43	−1.50 (−4.12, 8.03)	>.99
HRCT score <7	No.	–	8	–	6	–
	LCI	57.11 ± 25.53	1.50 (−0.09, 3.08)	0.06	−0.72 (−1.93, 0.50)	0.19
	MMEF predicted%	13.49 ± 2.84	9.38 (−2.96, 21.73)	0.12	−2.47 (−15.77, 10.83)	0.66
7 ≤ HRCT score < 13	No.	–	9	–	9	–
	LCI	19.40 (23.75)	−0.68 (−2.70, 1.35)	0.46	0.89 (−1.84, 3.61)	0.47
	MMEF predicted%	16.70 (1.55)	0.37 (−6.06, 6.80)	0.90	1.69 (−4.25, 7.63)	0.53
HRCT score ≥13	No.	–	5	–	5	–
	LCI	22.56 ± 5.61	1.62 (−10.60, 10.04)	>0.99	−1.33 (−4.38, 1.29)	0.31
	MMEF predicted%	14.82 ± 4.93	2.20 (−3.45, 5.89)	0.51	−1.50 (−4.02, 1.94)	0.39

95% CI: 95% confidence interval LCI: lung clearance index; MMEF: maximal mid-expiratory flow For baseline levels, data were expressed as mean ± standard deviation or otherwise median (interquartile range) if appropriate.

^*P value of exacerbation level compared with that of baseline levels.

^**P value of post-antibiotic treatment visit level compared with that of exacerbation levels.