Table 2.

Integration frequency near safe harbor criteria. Table showing the percentage of HIV-based vector integration sites relative to features used to define UNsafe harbors. These criteria are considered to be UNsafe: TSS, Oncogenes, miRNA encoding regions, Transcription units and ultra-conserved regions. The % integrations negatively associated with these 5 features is used to calculate a safety profile. Colors depict the nature of the association based on the highest and lowest value in the column. Asterisks depict a significant deviation from the DMSO treated control dataset (Pearson's Chi-square test; ***, p-values < 0.005; **, p-values < 0.05; *, p-values < 0.5).TSS, Transcription start sites; UCR, Ultra conserved regions.