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. 2016 Jun 13;2(6):401–408. doi: 10.1021/acscentsci.6b00113

Figure 8.

Figure 8

isoTOP-ABPP of Jurkat cell lysate treated with dimer, warhead, or unsaturated monomers. Jurkat cell lysate was treated with dimer (25 μM), warhead (50 μM), or unsaturated monomers (50 μM) for 1 h at ambient temperature. isoTOP-ABPP was performed as previously described.41,43 Shown on x-axis are top-100 changing Cys-peptides for each tested compound, where change is defined as a high isoTOP-ABPP ratio (DMSO/compound).