Table 3.
Analysis of independent risk factors for E. coli resistance to amoxicillin, trimethoprim/sulfamethoxazole and ciprofloxacin
| Risk factor | Number | % | AMX | SXT | CIP | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Crude OR [95 %] | P value | Ajusted OR [95 %] | P value | OR [95 %] | P value | Ajusted OR [95o%] | P value | OR [95 %] | P value | Ajusted OR [95 %] | P value | |||
| Sex - Male | 124 | 19.9 | 1.5 [1.1–2.3] | 0.04 | 1.4 [0.8–2.2] | 0.21 | 1.6 [0.9–2.7] | 0.09 | ||||||
| Age category | ||||||||||||||
| less than 40 years | 168 | 26.9 | Ref | Ref | Ref | |||||||||
| 40–59 years | 141 | 23.7 | 0.9 [0.5–1.4] | 0.55 | 1.1 [0.6–2.0] | 0.81 | 2.7 [1.1–6.9] | 0.03 | ||||||
| 60–69 years | 115 | 21.2 | 1.1 [0.7–1.8] | 0.66 | 1.9 [1.1–3.4] | 0.03 | 4.5 [1.9–10.9] | <0.01 | ||||||
| 70 year and more | 176 | 28.2 | 1.2 [0.7–1.8] | 0.45 | 1.9 [1.1–3.3] | 0.03 | 4.8 [2.1–11.3] | <0.01 | ||||||
| Presence of clinical signs | 147 | 73.5 | 0.6 [0.4–1] | 0.07 | 0.5 [0.2–0.9] | 0.03 | 0.9 [0.3–3.1] | 0.87 | 1.2 [0.6–2.6] | 0.59 | ||||
| Chronic illness | 56 | 26.7 | 1.1 [0.7–1.9] | 0.64 | 1.1 [0.3–3.7] | 0.91 | 1.4 [0.7–2.7] | 0.41 | ||||||
| Prior (3 months) UTI | 52 | 24.8 | 1.8 [1–3.2] | 0.04 | 2.3 [1.1–4.9] | 0.02 | 3.1 [1–10.1] | 0.05 | 5.4 [2.7–11] | <0.01 | 5.1 [2.5–10.3] | <0.01 | ||
| Prior (12 months) hospitalization | 32 | 15.2 | 2.2 [1.2–4.4] | 0.02 | 5.1 [1.6–16.5] | <0.01 | 1.7 [0.8–3.7] | 0.2 | ||||||
| Prior (6 months) urinary catheter | 14 | 7 | 11.6 [2.7–50.6] | <0.01 | 8.8 [1.9–40.8] | <0.01 | 10.1 [2.5–40.4] | <0.01 | 11.1 [2.4–51.6] | <0.01 | 2.1 [0.7–5.7] | 0.16 | ||
| Prior (6 months) antibiotic exposure | 14 | 21.4 | 1.4 [0.8–2.4] | 0.26 | 3.8 [1.1–12.9] | 0.03 | 4 [0.9–18.9] | 0.07 | 2.4 [1.2–4.9] | 0.02 | ||||
Only significant adjusted OR are presented
OR odds ratio, UTI urinary tract infection
*Significant difference (P < 0.05)