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. 2016 Jun 24;17:257. doi: 10.1186/s12859-016-1123-5

Table 1.

Table comparing the type I error of the joint score test statistic, U ψ with tissue-by-tissue (TBT) analysis, MetaTissue (MT) model (FE = Fixed Effects model; RE = Random Effects model) and multivariate Bayesian Model Averaging. Note that all the results are based on 5,000 simulations on 100 observations at a nominal level of α=0.05

Number of tissues = 5 Number of tissues = 10
MAF TBT M T(F E) MT(RE) BMA U ψ TBT M T(F E) MT(RE) BMA U ψ
0.05 0.0422 0.0410 0.0488 0.0488 0.0456 0.0434 0.0362 0.0404 0.0392 0.0416
0.10 0.0476 0.0442 0.0510 0.0488 0.0494 0.0512 0.0368 0.0472 0.0448 0.0480