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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Cancer Lett. 2015 Nov 27;371(1):117–124. doi: 10.1016/j.canlet.2015.10.040

Figure 2. In vivo effect of myeloid cell depletion on MM growth and chemosensitivity.

Figure 2

(A–C) Proportion and absolute number of BM CD11b+Gr1+ cells (A), indicated populations of myeloid cells (B), or lymphocytes (C) in CD11b-DTR-chimeras 48h after DT injection (n=3). (D) DP42 tumors were established in CD11b-DTR chimeras. Treatment with doxorubicin (dox, Pfizer, i.v., 4 mg/kg every 4 days) started 10 days after tumor cell inoculation (n=11–14 per group). Survival of mice was determined. ** - p<0.005; and *** - p< 0.001.