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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Cancer Lett. 2015 Nov 27;371(1):117–124. doi: 10.1016/j.canlet.2015.10.040

Figure 5. Effect of human neutrophils on MM.

Figure 5

(A) Proportion of different myeloid cell populations in BM of healthy donors and patients with MM was determined by flow cytometry and presented as a frequency of DAPI-negative cells. (B,C) Human MM cell lines were cultured with or without IMCs from BM of healthy donors (n=4–5), or MDSCs (n=4–5), neutrophils (Neu) (n=5), or T cells (n=6) isolated from BM of patients with MM. Cells were then treated with doxorubicin (B) or melphalan (C) followed by detection of apoptosis. * - p<0.05; ** - p<0.01; *** - p<0.0005; **** - p<0.0001.