Table 2.
Sites of infection in patients with STAT1 GOF mutations
| Type of infections | Patients (%) |
|---|---|
| n = 274 | |
| Mucocutaneous fungal infections | 268 (98) |
| Oropharyngeal mycosis | 254 (93) |
| Cutaneous mycosis | 155 (57) |
| Esophageal/genital mycosis | 153 (56) |
| Onychomycosis | 153 (56) |
| Aphtous stomatitis | 125 (46) |
| Scalp mycosis | 55 (20) |
| Invasive fungal infections | 28 (10) |
| Invasive candidiasis | 10 (4) |
| Other invasive infections | 20 (7) |
| Bacterial infections* | 202 (74) |
| LRI | 129 (47) |
| ENT | 121 (44) |
| Skin | 77 (28) |
| Others† | 24 (9) |
| Mycobacterial infections | 17 (6) |
| Lung disease | 6 (2) |
| Adenitis/skin disease | 5 (2) |
| Disseminated disease | 6 (2) |
| Viral infections* | 103 (38) |
| Cutaneous | 88 (32) |
| Systemic | 23 (8) |
ENT: ear, nose, and throat.
*
Probable or proven bacterial/viral infection.
†
Severe acute gastroenteritis, septicemia, bone and joint infections, recurrent urinary tract infections.