Standard dosage	5 mg to 10 mg a day, 23 mg daily dose available, but patients may not tolerate side effects
Contraindications	caution in patients with bradycardia, cardiac conduction disorder, severe ob- structive pulmonary disease, peptic ulcer disease; caution when used with beta- blockers
Main drug interactions	beta-blockers, antagonistic effects with anticholinergics, metabolized by CYP450 3A4
Main side effects	nausea, diarrhea, insomnia, fatigue, vomit, cramps, vivid dreams, bradycardia
Cost	inexpensive unless 23 mg dose used
Standard dosage	4 mg twice daily to 12 mg twice daily; extended-release 8 mg daily to 24 mg daily
Contraindications	caution in patients with bradycardia, cardiac conduction disorder, severe ob- structive pulmonary disease, peptic ulcer disease; caution when used with beta- blockers
Main drug interactions	beta-blockers, antagonistic effects with anticholinergics, CYP2D6 or CYP3A4 inhibitors may increase serum levels of galantamine
Main side effects	nausea, diarrhea, insomnia, fatigue, vomit, cramps, vivid dreams, bradycardia
Cost	inexpensive
Standard dosage	starting at 1.5 mg twice a day, titrate to 6 mg twice a day. Transdermal patch starts with 4.6 mg per 24 h, increased to 13.3 mg per 24 h after 4 weeks.
Contraindications	caution in patients with bradycardia, cardiac conduction disorder, severe ob- structive pulmonary disease, peptic ulcer disease; caution when used with beta- blockers
Main drug interactions	beta-blockers, antagonistic effects with anticholinergics
Main side effects	nausea, diarrhea, insomnia, fatigue, vomit, cramps, vivid dreams, bradycardia
Cost	inexpensive, transdermal system may be slightly more expensive