Standard dosage	oral 25 mg daily to maximum 400 mg daily divided by two or three times a day dosing
Contraindication	hypokalemia, hypomagnesemia, congenital QTc prolongation
Main drug interactions	CYP450 3A4 inducers may require lowered dose of quetiapine; conversely, 3A4 inducers may require increased dose
Main side effects	sedation, weight gain, headache, extrapyramidal symptoms, raised cholesterol, QTc prolongation, dry mouth, hypotension, neuroleptic malignant syndromes, cataracts
Special points	sedative properties may be helpful for patients with insomnia as main com- plaint, lower risk of extrapyramidal side effects
Cost	expensive compared to other oral agents