Standard dosage	20 mg/day dose used in study
Contraindication	agitated state, advanced arteriorsclerosis, symptomatic cardiovascular disease, history of drug dependency, glaucoma, moderate to severe hypertension, hyperthyroidism
Main drug interactions	concomitant use with MAOI may result in hypertensive crisis
Main side effects	tachycardia, myocardial infarction, Raynaud’s, peripheral vascular disease, ce- rebrovascular accident, intracranial hemorrhage, lowered seizure threshold, aggressive behavior, psychotic disorder, drug dependence
Special points	schedule II medication, high potential for abuse
Cost	expensive compared to other oral agents
Standard dosage	40 mg dose used in study
Contraindication	glaucoma, marked agitation, motor tics, Tourette’s syndrome, severe anxiety, severe cardiovascular disease, hyperthyroidism
Main drug interactions	concomitant use of MAOIs, anorexiants
Main side effects	decrease in appetite, insomnia, peripheral vascular disease, Raynaud’s, lowered seizure threshold, priapism, mania, drug dependence
Special points	schedule II medication, high risk for abuse
Cost	expensive compared to other oral agents