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. Author manuscript; available in PMC: 2016 Jun 24.
Published in final edited form as: Curr Treat Options Neurol. 2014 Nov;16(11):319. doi: 10.1007/s11940-014-0319-0
Standard dosage 25/100 mg, 1 – 3 tabs three times daily
Contraindications concomitant use of MAOi, narrow-angle closure glaucoma, history of
melanoma
Main drug interactions antipsychotics
Main side effects dyskinesia, orthostatic hypotension, nausea, vomiting, hallucinations, com-
pulsive behavior
Special points Start with 1/2 to 1 tablet dose three times daily and increase in increments
weekly until minimal dose required is achieved.
Carbidopa/levodopa competes with protein for absorption
Cost inexpensive