Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Hematologic laboratory test abnormalities in the COMFORT trials during randomized treatment
| COMFORT-I [33] | COMFORT-II [34] | |||
|---|---|---|---|---|
|
| ||||
| Event, Percentage of patients | Ruxolitinib (n = 155) | Placebo (n = 151) | Ruxolitinib (n = 146) | BAT (n = 73) |
| Anemia | ||||
| All grades | 96.1 | 86.8 | 96 | 94 |
| Grade ≥3 | 45.2 | 19.2 | 42 | 31 |
| Thrombocytopenia | ||||
| All grades | 69.7 | 30.5 | 68 | 29 |
| Grade ≥3 | 12.9 | 1.3 | 8 | 7 |
| Neutropenia | ||||
| All grades | 18.7 | 4.0 | NR | NR |
| Grade ≥3 | 7.1 | 2.0 | NR | NR |
BAT: Best available therapy; NR: Not reported.
