Table 1.
25(OH)D > 30 ng/ml |
25(OH)D 20 – 30 ng/ml |
25(OH)D < 20 ng/ml |
P-trend | |
---|---|---|---|---|
Weighted N | 8442 | 9944 | 7939 | |
Age | 64.8 (63.8,65.9) | 65.0 (64.0,66.0) | 64.1 (63.0,65.1) | 0.32 |
Male (%) | 51 | 46 | 36 | <0.001 |
Black (%) | 17 | 32 | 74 | <0.001 |
Body Mass Index (kg/m2) | 27.5 (26.9,28.1) | 29.0 (28.5,29.6) | 31.4 (30.6,32.2) | <0.001 |
Waist circumference (cm) | 91.9 (90.3, 93.4) | 95.0 (93.5, 96.4) | 100.5 (98.8, 102.3) | <0.001 |
Systolic blood pressure (mm Hg) | 125.0 (123.1,126.8) | 126.7 (125.1,128.3) | 130.7 (128.7,132.7) | 0.002 |
Diastolic blood pressure (mm Hg) | 74.8 (73.6,75.9) | 76.2 (75.3,77.2) | 78.6 (77.5,79.7) | <0.001 |
Less than high school education (%) | 6 | 11 | 18 | <0.001 |
Annual income < $20,000/year (%) | 13 | 13 | 28 | <0.001 |
Co-morbidities | ||||
Current smoking (%) | 12 | 11 | 19 | <0.001 |
Diabetes (%) | 10 | 20 | 33 | <0.001 |
Coronary heart disease (%) | 20 | 16 | 13 | <0.001 |
Atrial fibrillation (%) | 9 | 9 | 8 | 0.16 |
Chronic kidney disease (%) | 16 | 17 | 23 | <0.001 |
Left ventricular hypertrophy (%) | 7 | 6 | 11 | <0.001 |
Medication Use | ||||
Anti-hypertensives (%) | 51 | 55 | 68 | <0.001 |
Aspirin (%) | 50 | 39 | 38 | <0.001 |
Statins (%) | 33 | 31 | 33 | 0.72 |
Laboratory values | ||||
Calcium (mg/dL) | 9.3 (9.2,9.3) | 9.1 (9.0, 9.2) | 9.2 (9.1, 9.3) | 0.25 |
Phosphorus (mg/dL) | 3.5 (3.4, 3.6) | 3.5 (3.4, 3.5) | 3.5 (3.4, 3.5) | 0.94 |
Intact parathyroid hormone (pg/ml) | 35.5 [27.3, 44.7] | 40.1 [31.64, 50.0] | 50.1 [36.8, 71.5] | <0.001 |
Total cholesterol (mg/dL) | 187.7 (183.8, 191.6) | 192.9 (188.2, 197.5) | 193.0 (188.3,197.7) | 0.24 |
High-density lipoprotein (mg/dL) | 53.2 (51.1, 55.3) | 494. (48.3, 51.5) | 52.1 (50.2, 54.1) | 0.07 |
Low-density lipoprotein (mg/dL) | 113.1 (109.1, 117.1) | 110.0 (10.6,7, 113.3) | 115.9 (111.8, 119.9) | 0.16 |
Triglycerides (mg/dL) | 132.3 (123.1, 141.5) | 135.4 (127.4, 143.4) | 121.5 (115.0, 128.0) | 0.19 |
Abbreviations: 25(OH)D, 25-hydxovyitamin D; NT-proBNP, N-terminal pro B-type natriuretic peptide.