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. 2016 Jun 1;9(6):707–717. doi: 10.1242/dmm.023440

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© 2016. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 2. — CD80 expression on podocytes is essential for albuminuria. (A) Comparison of urinary albumin:creatinine ratios in BM chimeric mice given LPS or PBS. The key identifies BM donors and recipients (five mice per group). (B) CD80 levels in BM chimeric mice given LPS or PBS (five mice per group). ‘B6’ in panels A and B indicates B6.SJL. (C) Relative CD80 mRNA expression in E11 podocytes exposed to serum from B6 mice that had been treated as indicated (n=6, data from three independent experiments). (D) Relative CD80 mRNA expression in E11 podocytes exposed to serum from B6 and CD80^−/− mice given LPS or PBS (n=6, data from three independent experiments). The results represent mean±s.e.m. ND, not detectable; ns, not significant.