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. 2016 May 16;5(6):794–800. doi: 10.1242/bio.017798

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© 2016. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 2. — Silencing of leptin by leptin-targeted siRNA reduced cell proliferation in NSCLC A549 and 95D cells. (A,C) Growth curves calculated for A549 and 95D cells treated with leptin siRNA and control siRNA. (B,D) Ki67 expression A549 and 95D cells treated with siRNA transfection. Western blot analysis showed that Ki67 expression in cells treated with leptin siRNA was significantly lower than that of cells treated with control siRNA. Data expressed as mean± s.e.m.; *P<0.05 compared to control siRNA-treated cells.