Table 5.
Total Modified Sharp van der Heijde (mvdH-S) radiographic scores (hands+feet) at baseline and week 48 (evaluable patient population)
| Tight control N (%) | Standard care N (%) | Total N (%) | |
|---|---|---|---|
| Erosive disease at baseline? | |||
| Yes | 25 (26.6%) | 24 (23.8%) | 49 (25.1%) |
| No | 69 (73.4%) | 77 (76.2%) | 146 (74.9%) |
| Total | 94 (100%) | 101 (100%) | 195 (100%) |
| Erosive disease at week 48? | |||
| Yes | 29 (32.6%) | 25 (28.7%) | 54 (30.7%) |
| No | 60 (67.4%) | 62 (71.3%) | 122 (69.3%) |
| Total | 89 (100%) | 87 (100%) | 176 (100%) |
| mvdH-S Erosion Score | |||
| Baseline | |||
| Median (IQR) | 0.0 (0.0, 1.0) | 0.0 (0.0, 0.0) | 0.0 (0.0, 1.0) |
| N | 94 | 101 | 195 |
| Week 48 | |||
| Median (IQR) | 0.0 (0.0, 1.0) | 0.0 (0.0, 1.0) | 0.0 (0.0, 1.0) |
| N | 89 | 87 | 176 |
| Joint space narrowing (JSN) at baseline? | |||
| Yes | 81 (86.2%) | 84 (83.2%) | 165 (84.6%) |
| No | 13 (13.8%) | 17 (16.8%) | 30 (15.4%) |
| Total | 94 (100%) | 101 (100%) | 195 (100%) |
| Joint space narrowing (JSN) at week 48? | |||
| Yes | 78 (87.6%) | 73 (83.9%) | 151 (85.8%) |
| No | 11 (12.4%) | 14 (16.1%) | 25 (14.2%) |
| Total | 89 (100%) | 87 (100%) | 176 (100%) |
| mvdH-S JSN Score | |||
| Baseline | |||
| Median (IQR) | 8.0 (3.0, 16.0) | 8.0 (2.0, 13.0) | 8.0 (2.0, 15.0) |
| N | 94 | 101 | 195 |
| Week 48 | |||
| Median (IQR) | 8.0 (4.0, 15.0) | 6.0 (2.0, 15.0) | 8.0 (2.0, 15.0) |
| N | 89 | 87 | 176 |
| Total mvdH-S Heidje Score (Erosion + JSN) | |||
| Baseline | |||
| Median (IQR) | 9.0 (3.0, 17.0) | 8.0 (2.0, 16.0) | 8.0 (2.0, 16.0) |
| N | 94 | 101 | 195 |
| Week 48 | |||
| Median (IQR) | 8.0 (4.0, 16.0) | 6.0 (2.0, 17.0) | 8.0 (3.0, 17.0) |
| N | 89 | 87 | 176 |
| Total mvdH-S Heidje Score (Erosion + JSN), median improvement (IQR) | 0.0 (-2.0, 0.5) | 0.0 (-2.0, 0.0) | 0.0 (-2.0, 0.0) |
| Non-missing N (total N) | 84 | 85 | 169 |
Summaries correspond to those patients with non-missing data at baseline and week 48.