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. 2016 Jun 24;11(6):e0157517. doi: 10.1371/journal.pone.0157517

Table 4. Multivariable logistic regression models evaluating the association between NAFLD Fibrosis Score risk categories and dichotomous cardiometabolic risk factors.

Low risk advanced fibrosis Indeterminate risk advanced fibrosis High risk advanced fibrosis
OR (95%CI) OR (95%CI) P-value OR (95%CI) P-value
Hypertension (yes vs no)
MV* Reference 1.06 (0.71,1.59) 0.77 3.06 (1.33,7.04) 0.009
MV + BMI Reference 0.87 (0.56,1.36) 0.55 2.05 (0.83,5.07) 0.12
MV + VAT Reference 0.90 (0.59,1.37) 0.62 2.19 (0.93,5.18) 0.07
Low HDL cholesterol (yes vs no)
MV* Reference 1.27 (0.84,1.93) 0.26 1.45 (0.72,2.89) 0.30
MV + BMI Reference 1.23 (0.78,1.93) 0.37 1.35 (0.62,2.94) 0.45
MV + VAT Reference 1.14 (0.74,1.75) 0.55 1.15 (0.55,2.38) 0.71
High Triglycerides (yes vs no)
MV* Reference 1.46 (0.98,2.18) 0.06 2.03 (0.99,4.17) 0.05
MV + BMI Reference 1.22 (0.79,1.89) 0.36 1.41 (0.64,3.12) 0.39
MV + VAT Reference 1.25 (0.82,1.88) 0.30 1.46 (0.69,3.08) 0.32

NAFLD, Non-alcoholic fatty liver disease; OR, odds ratio; HDL, high density lipoprotein; BMI, body mass index; VAT, visceral adipose tissue.

*Multivariate model (MV): Covariate adjustment included age, sex, smoking status (current vs no), and drinks per day.