Table 4. Multivariable logistic regression models evaluating the association between NAFLD Fibrosis Score risk categories and dichotomous cardiometabolic risk factors.
Low risk advanced fibrosis | Indeterminate risk advanced fibrosis | High risk advanced fibrosis | |||
---|---|---|---|---|---|
OR (95%CI) | OR (95%CI) | P-value | OR (95%CI) | P-value | |
Hypertension (yes vs no) | |||||
MV* | Reference | 1.06 (0.71,1.59) | 0.77 | 3.06 (1.33,7.04) | 0.009 |
MV + BMI | Reference | 0.87 (0.56,1.36) | 0.55 | 2.05 (0.83,5.07) | 0.12 |
MV + VAT | Reference | 0.90 (0.59,1.37) | 0.62 | 2.19 (0.93,5.18) | 0.07 |
Low HDL cholesterol (yes vs no) | |||||
MV* | Reference | 1.27 (0.84,1.93) | 0.26 | 1.45 (0.72,2.89) | 0.30 |
MV + BMI | Reference | 1.23 (0.78,1.93) | 0.37 | 1.35 (0.62,2.94) | 0.45 |
MV + VAT | Reference | 1.14 (0.74,1.75) | 0.55 | 1.15 (0.55,2.38) | 0.71 |
High Triglycerides (yes vs no) | |||||
MV* | Reference | 1.46 (0.98,2.18) | 0.06 | 2.03 (0.99,4.17) | 0.05 |
MV + BMI | Reference | 1.22 (0.79,1.89) | 0.36 | 1.41 (0.64,3.12) | 0.39 |
MV + VAT | Reference | 1.25 (0.82,1.88) | 0.30 | 1.46 (0.69,3.08) | 0.32 |
NAFLD, Non-alcoholic fatty liver disease; OR, odds ratio; HDL, high density lipoprotein; BMI, body mass index; VAT, visceral adipose tissue.
*Multivariate model (MV): Covariate adjustment included age, sex, smoking status (current vs no), and drinks per day.