Table 2. Mutation frequency as a function of mutation type.
Mutation type | Mutation frequency |
---|---|
A>C/T>G | 4.4 x 10−7 |
C>G/G>C | 1.1 x 10−6 |
A>T/T>A | 1.4 x 10−6 |
A>G/T>C | 3.3 x 10−6 |
C>T/G>A (non-CpG) | 1.7 x 10−5 |
G>T /C>A | 2.2 x 10−5 |
C>T/G>A (CpG) | 7.4 x 10−5 |
Data for the PTPN11, MECP2, and FGFR3 experiments combined. Unlike Fig 3, the mutation frequencies are not the sums of all three possible mutations at each base pair.