Fig. 2.
AlCl3 does not stimulate THP-1 cells to secret IL-1β. Differentiated THP-1 cells were incubated with various concentrations of aluminum as AlCl3, AH-NPs, or Alhydrogel® for 6 h in the presence of LPS, and IL-1β levels in cell culture medium were measured using the HEK-Blue™ IL-1β cells-QUANTI-Blue™ assay. a,b p ≤ 0.05, AH-NPs or Alum vs. Control at aluminum concentrations ≥ 25 µg/ml.