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. 2016 Jun 24;11(6):e0156911. doi: 10.1371/journal.pone.0156911

Table 3. Mean Baseline and Change From Baseline (intervention) QLQ-C30 Scores.

Subscales Baseline (pre intervention) Follow Up (post intervention)
Intervention Group Control Group Intervention Group (Mean Change–p) Control Group (Mean Change–p)
Global QOL* 54.9 (22.7) 51.9 (22.3) +9.5 <0.0001 -10.7 <0.0001
Functional Scales*
Physical Functioning* 66.5 (21.4) 68.1 (23.2) +8.7 <0.0001 -3.4 <0.0001
Role functioning 69.2 (22.8) 71.1 (29.5) +2.1 <0.0001 -1.5 <0.0001
Emotional functioning 59.8 (22.1) 63.3 (23.8) +5.6 <0.0001 -4.2 <0.0001
Cognitive functioning 83.2 (20.1) 81.1 (20.3) +0.3 0.009 -0.2 0.177
Social functioning 76.4 (25.8) 79.4 (24.5) +1.0 0.036 -1.7 <0.0001
Symptom Scales**
Fatigue 67.8 (19.6) 73.1 (21.8) -17.1 <0.0001 +7.6 <0.0001
Nausea and Vomiting 34.5 (25.3) 37.7 (24.5) -8.4 <0.0001 +2.2 <0.0001
Pain 45.9 (26.1) 44.9 (28.3) -11.3 <0.0001 -1.0 0.0004
Dyspnea 28.2 (27.1) 29.2 (27.5) +0.6 0.0044 +0.4 0.00034
Insomnia 21.2 (27.0) 19.6 (26.2) -1.3 <0.0001 +0.9 <0.0001
Appetite loss 21.4 (29.3) 20.9 (27.8) -1.0 0.00065 +3.3 <0.0001
Constipation 20.7 (23.6) 21.6 (24.4) +0.8 <0.0001 +1.0 <0.0001
Diarrhea 15.5 (25.7) 14.7 (24.3) -1.5 <0.0001 -0.3 <0.0001
Financial difficulties 32.1 (28.2) 32.0 (28.1) -2.4 <0.0001 -2.0 <0.0001

*Higher scores indicate better global Quality of Life and functioning

**Higher scores indicate worse symptoms

† Paired t-test