Table 3. Mean Baseline and Change From Baseline (intervention) QLQ-C30 Scores.
Subscales | Baseline (pre intervention) | Follow Up (post intervention) | ||||
---|---|---|---|---|---|---|
Intervention Group | Control Group | Intervention Group (Mean Change–p†) | Control Group (Mean Change–p†) | |||
Global QOL* | 54.9 (22.7) | 51.9 (22.3) | +9.5 | <0.0001 | -10.7 | <0.0001 |
Functional Scales* | ||||||
Physical Functioning* | 66.5 (21.4) | 68.1 (23.2) | +8.7 | <0.0001 | -3.4 | <0.0001 |
Role functioning | 69.2 (22.8) | 71.1 (29.5) | +2.1 | <0.0001 | -1.5 | <0.0001 |
Emotional functioning | 59.8 (22.1) | 63.3 (23.8) | +5.6 | <0.0001 | -4.2 | <0.0001 |
Cognitive functioning | 83.2 (20.1) | 81.1 (20.3) | +0.3 | 0.009 | -0.2 | 0.177 |
Social functioning | 76.4 (25.8) | 79.4 (24.5) | +1.0 | 0.036 | -1.7 | <0.0001 |
Symptom Scales** | ||||||
Fatigue | 67.8 (19.6) | 73.1 (21.8) | -17.1 | <0.0001 | +7.6 | <0.0001 |
Nausea and Vomiting | 34.5 (25.3) | 37.7 (24.5) | -8.4 | <0.0001 | +2.2 | <0.0001 |
Pain | 45.9 (26.1) | 44.9 (28.3) | -11.3 | <0.0001 | -1.0 | 0.0004 |
Dyspnea | 28.2 (27.1) | 29.2 (27.5) | +0.6 | 0.0044 | +0.4 | 0.00034 |
Insomnia | 21.2 (27.0) | 19.6 (26.2) | -1.3 | <0.0001 | +0.9 | <0.0001 |
Appetite loss | 21.4 (29.3) | 20.9 (27.8) | -1.0 | 0.00065 | +3.3 | <0.0001 |
Constipation | 20.7 (23.6) | 21.6 (24.4) | +0.8 | <0.0001 | +1.0 | <0.0001 |
Diarrhea | 15.5 (25.7) | 14.7 (24.3) | -1.5 | <0.0001 | -0.3 | <0.0001 |
Financial difficulties | 32.1 (28.2) | 32.0 (28.1) | -2.4 | <0.0001 | -2.0 | <0.0001 |
*Higher scores indicate better global Quality of Life and functioning
**Higher scores indicate worse symptoms
† Paired t-test