Table 5. Linear Mixed Models of Global QoL and PAIN, for the effect of intervention group.

Adjusted for covariates.

	Dependent variable:
	Global QoL		PAIN Scale (1..10)
Source	F	Sig.	F	Sig.
Intercept	546,95	<0,0001	0,34	<0,0001
Intervention group	17,05	<0,0001	16,47	<0,0001
Time (Pre-Post)	1,35	0,2459	0,18	0,6750
Intervention group * Time	29,64	<0,0001	13,55	0,0003
Vomiting (INVR)	2,25	0,1341	0,38	0,5384
Anxiety (SAS)	3,82	0,0514	14,56	0,0002
Depression (BDI-II)	11,76	0,0006	10,73	0,0012
Fatigue (CFS)	30,94	<0,0001	20,59	<0,0001

Covariance Structure: Unstructured

Restricted Maximum Likelihood Estimation (REML)

Coding: Intervention group = 1, Control group = 0