Table 1. Stochastic R* parameters.
|
Symbol |
Description |
Value |
Units |
|---|---|---|---|
| Model 1: Conventional graded R* shut-off | |||
|
N |
Number of sites for phosphorylation |
6 |
|
|
M |
Minimum phosphates for Arr binding |
3 |
|
| νmax |
Maximal rate constant of phosphorylation |
80 |
s−1 |
| μ |
Rate constant of Arr binding |
20 |
s−1 |
| ωP |
Exponential factor for phosphorylation |
1 |
|
| ωG | Exponential factor for R* activity | 1 |
| Model 2: Binary R* shut-off Case 1: All rate constants equal | |||
|---|---|---|---|
|
N |
Number of sites for phosphorylation |
Any, ≥3 |
|
|
M |
Minimum phosphates for Arr binding |
3 |
|
| ν, μ | Rate constants for all reactions | 60 | s−1 |
| Model 3: Three-state R* shut-off Case 1: All rate constants equal | |||
|---|---|---|---|
|
N |
Number of sites for phosphorylation |
Any, ≥3 |
|
|
M |
Minimum phosphates before Arr binding |
3 |
|
| ν, κ, μ |
Rate constants for all reactions |
60 |
s−1 |
| ρlow | Fractional R* activity in low-activity state | 0.1 |