Table 1. Model Parameters.

(#1) Sanes [51] reported that the number of excitatory subthreshold inputs was 9.6 ± 2.8 in gerbils, which serves as the lower bound of the total number of excitatory inputs. The MSO neuron, which has a similar anatomical structure to the LSO neuron, receives a few times more excitatory inputs than inhibitory inputs [53]. Assuming a similar ratio, 20 excitatory inputs (derived from 8 inhibitory inputs) would be reasonable. (#2) Measured membrane time constants of gerbil LSO cells were 1.1 ± 0.4 ms and minimum durations of excitatory synaptic inputs were 1.5 ± 0.8 ms [51]. We assumed that these values roughly limit the maximum width of the coincidence window. (#3) Based on the measured minimum durations of inhibitory synaptic inputs of 3.2 ± 1.7 ms in gerbils [51], we assumed the inhibition window to be twice as long as the coincidence window. (#4) As far as we know, there is no direct measurement available. See Discussion for more information on relevant experimental values.

Parameter	Default value	Simulated range	Relevant experimental values
Number of excitatory inputs Mex	20	(fixed)	(#1)
Number of inhibitory inputs Minh	8	(fixed)	8.2 ± 3.5 (gerbils) [51]
Coincidence threshold θ	8	5–11	9.6 ± 2.8 (gerbils) [51]
Coincidence window W	0.8 ms	0.4–1.3 ms	(#2)
Refractory period T	1.6 ms	0.8–2.4 ms	1.1–2.8 ms (cats) [52]
Inhibition window Δ	1.6 ms	0.8–2.4 ms	0.8–2.0 ms (rats) [30] (#3)
Threshold increase δ	2	0–8	(#4)