Table 3. Immunohistochemistry analysis of angiogenesis, inflammation and collagen metabolism.
| IL-1* | TNF* | MMP-2* | CD-31** | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||||
| PP (SD) | SHAM (SD) | p | PP (SD) | SHAM (SD) | P | PP (SD) | SHAM (SD) | p | PP (SD) | SHAM (SD) | |
| 4 days | 50.07 (13.47) | 32.36 (20.31) | 0.08 | 56.42 (7.61) | 31.98 (11.92) | <0.0001 | 54.19 (25.24) | 31.65 (9.07) | 0.066 | N/A | N/A |
| 30 days | 25.66 (14.41) | 27.09 (18.84) | 0.08 | 40.65 (15.49) | 34.39 (11.92) | 0.420 | 29.98 (14.77) | 44.57 (14.53) | 0.024 | 19.64 (9.43) | 16.54 (7.94) |
| p | 0.010 | 0.010 | 0.0161 | 0.523 | 0.018 | 0.058 | PP x SHAM | 0.587 | |||
*Mean percentage of the area marked by the antibody relative to the field** Average number of vessels per field SD = Standard deviation