Table 2.
Table showing Mean CD4, sensitivity, specificity, positive likelihood ratio (PLR) and negative likelihood ratio (NLR) with 95% confidence intervals for different levels of cut-off values for total lymphocyte counts (TLC), haemoglobin (Hb) levels and erythrocyte sedimentation rates (ESR) among the study specimens while predicting CD4+ T cell counts <200/mm3
| Mean CD4 (cells/mm3) | Sensitivity (%) | Specificity (%) | PLR | NLR | ||
|---|---|---|---|---|---|---|
| TLC (cells/mm3) | ||||||
| 1200 | 151.56 | 9.4 (4.8-18.9) | 100 (97.5-100) | * | 1.1 | (1.02-1.19) |
| 1500 | 241.08 | 18.8 (11-29.9) | 96 (91.6-98.2) | 4.72 (1.85-12.02) | 0.85 | (0.75-0.96) |
| 1850 | 251.57 | 35.9 (25.3-48.1) | 84.8 (78.2-89.6) | 2.36 (1.43-3.88) | 0.76 | (0.62-0.92) |
| Hb (g/dL) >10 | 268.83 | 20.3 (12.3-31.7) | 92.7 (87.4-95.9) | 2.79 (1.32-5.89) | 0.86 | (0.75-0.98) |
| >11 | 282.7 | 31.3 (21.2-43.4) | 82.8 (75.9-87.9) | 1.82 (1.09-3) | 0.83 | (0.69-0.99) |
| >12 | 281.26 | 54.7 (42.6-66.3) | 72.2 (64.6-78.8) | 1.97 (1.39-2.76) | 0.63 | (0.47-0.84) |
| ESR (mm fall after 1 hour) | ||||||
| >10 | 312.63 | 89.7 (79.2-95.2) | 19 (13.5-26.2) | 1.11 (0.96-1.25) | 0.54 | (0.24-1.24) |
| >20 | 294 | 81 (69.2-89.1) | 48.9 (41-56.9) | 1.59 (1.29-1.94) | 0.39 | (0.22-0.68) |
| >30 | 296.31 | 55.2 (42.5-67.3) | 66.7 (58.7-73.8) | 1.66 (1.19-2.29) | 0.67 | (0.49-0.92) |
*
Not measurable since the divisor is zero