Table 3.
Table showing Mean CD4, sensitivity, specificity, positive likelihood ratio (PLR) and negative likelihood ratio (NLR) with 95% confidence intervals for different levels of cut-off values for total lymphocyte counts (TLC), haemoglobin (Hb) levels and erythrocyte sedimentation rates (ESR) among the study specimens while predicting CD4+ T cell counts < 350/mm3
| Mean CD4 (cells/mm3) | Sensitivity (%) | Specificity (%) | PLR | NLR | |
|---|---|---|---|---|---|
| TLC (cells/mm3) | |||||
| 1200 | 151.56 | 6.1 (3.1-11.6) | 98.8 (93.6-99.8) | 5.13 (0.65-40.28) | 0.95 (0.9-0.99) |
| 1500 | 241.08 | 11.5 (7.1-18) | 90.5 (82-95.1) | 1.2 (0.53-2.71) | 0.98 (0.89-1.07) |
| 1850 | 251.57 | 25.2 (18.5-33.3) | 84.5 (75-90.7) | 1.62 (0.91-2.9) | 0.89 (0.77-1.01) |
| 2100 | 266.57 | 35.9 (28.2-44.4) | 72.6 (62.3-81) | 1.31 (0.86-1.99) | 0.88 (0.74-1.06) |
| 2400 | 288.56 | 57.3 (48.7-65) | 52.4 (41.8-62.7) | 1.2 (0.92-1.57) | 0.81 (0.61-1.08) |
| Hb (g/dL) | |||||
| >10 | 268.83 | 12.7 (8.1-19.4) | 92.6 (84.8-96.6) | 1.71 (0.7-4.17) | 0.94 ((0.86-1.03) |
| >12 | 282.7 | 40.3 (32.4-48.8) | 72.8 (62.3-81.3) | 1.48 (0.98-2.24) | 0.82 (0.68-0.99) |
| >14 | 281.26 | 79.1 (71.5-85.1) | 33.3 (24-44.2) | 1.19 (0.99-1.42) | 0.63 (0.39-0.98) |
| ESR (mm fall after 1 hour) | |||||
| >10 | 312.63 | 87.2 (80,2-91.1) | 21.3 (13.7-31.4) | 1.1 (0.97-1.26) | 0.6 (0.32-1.12) |
| >20 | 294 | 64 (55.3-71.9) | 50 (39.3-60.7) | 1.28 (0.99-1.65) | 0.72 (0.52-0.99) |
| >30 | 296.31 | 43.2 (34.9-51.9) | 67.5 (56.6-76-8) | 1.33 (0.91-1.93) | 0.84 (0.67-1.04) |