Table 1.
Investigation chart.
| At admission | After first surgery | Before first dose of rFVIIa | After rFVIIa | After second surgery and second dose of rFVIIa | |
|---|---|---|---|---|---|
| Hb (g/dL) | 14 | 9 | 6.6 | − | 10 |
| Serum bilirubin (mg/dL) | 14 | 11.4 | − | − | 13 |
| AST/ALT (U/L) | 104/394 | 334/72 | − | − | − |
| Prothrombin time (sec) | 12/23 | 12/30 | 12/40 | 12/15 | 12/9.7 |
| INR | 2.6 | 4 | 6 | 1.3 | 0.73 |
| PTTK (sec) | 30/40 | 30/38 | 30/62 | 30/33 | 30/29 |
| Platelet count (mm3) | − | 140,000 | 40,000 | 80,000 | 98,000 |
| FDP (ng/dL) | 6 | − | − | > 80 | |
| Fibrinogen (mg/dL) | 275 | − | 200 | − | 120 |
| D dimer (ng/dL) | 6 | − | 8 | > 40 |
Hb: haemoglobin, AST: aspartate aminotransferase, ALT: alanine aminotransferase, INR: international normalized ratio, PPTK: prothrombin time with activated thromboplastin with kaolin, FDP: fibrin degradation products.