Table 1.

Primary and secondary genetic events that can be identified by FISH

Primary genetic events			Secondary genetic events
IgH translocation	Gene(s)	Frequency (%)	Deletion	Gene(s)	Frequency (%)
t(4;14)	FGFR3/MMSET	15	1p	CDKN2C, FAF1, FAM46C	30
t(6;14)	CCND3	4	6q		33
t(11;14)	CCND1	20	8p		25
t(14;16)	MAF	4	13	RB1, DIS3	44
t(14;20)	MAFB	1	11q	BIRC2/BIRC3	7
			14q	TRAF3	38
			16q	WWOX, CYLD	35
			17p	TP53	7
Hyperdiploidy			Gain
Trisomies of chromosomes 3, 5, 7, 9, 11, 15, 19, 21	NA	50	1q	CKS1B, ANP32E	40