Figure 2.
Cumulative incidence of relapse stratified by year of diagnosis. Unadjusted incidence (2A) shows more relapses occur in patients diagnosed in later time periods, but no difference is seen after adjusting for baseline variables (2B). Adjusted for age, diagnosis, ANCA type, site, baseline serum creatinine, joint/upper respiratory/skin involvement, and duration of cyclophosphamide use. Time period 1985–1989 combined with time period 1990–1994 due to missing cyclophosphamide data in the 1985–1989 group.