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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: J Low Genit Tract Dis. 2016 Jul;20(3):218–223. doi: 10.1097/LGT.0000000000000206

Table 3. Clinical performance of the cervical cancer screening tests using a CIN2+ threshold.

VIA DC Xpert HPV OncoE6
True positive 15 19 28 10
False positive 14 20 66 1
True negative 153 147 100 166
False negative 16 13 4 22
Sensitivity (95% CI) 48% (30-67%) 59% (41-76%) 88% (71-97%) 31% (16-50%)
Specificity (95% CI) 92% (86-95%) 88% (82-93%) 60% (52-68%) 99% (97-100%)
PPV (95% CI) 52% (33-71%) 49% (32-65%) 30% (21-40%) 91% (59-100%)
NPV (95% CI) 91% (85-95%) 92% (87-96%) 96% (90-99%) 88% (83-93%)
PLR (95% CI) 10 (4-25) 5 (3-8) 2 (2-3) 52 (7-394)
NLR (95% CI) 0.6 (0.4-0.8) 0.5 (0.3-0.7) 0.2 (0.1-0.5) 0.7 (0.5-0.9)
OR (95% CI) 10 (4-25) 11 (4-25) 11 (4-30) 76 (12-.)

VIA: visual inspection with acetic acid; DC: digital cervicography; 95% CI: 95% confidence interval; PPV: positive predictive value; NPV: negative predictive value; PLR: positive likelihood ratio; NLR: negative likelihood ratio; OR: odds ratio