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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: J Low Genit Tract Dis. 2016 Jul;20(3):218–223. doi: 10.1097/LGT.0000000000000206

Table 4. Clinical performance of the cervical cancer screening tests using a CIN3+ threshold.

VIA DC Xpert HPV OncoE6
True positive 12 15 18 8
False positive 17 24 76 3
True negative 162 155 102 176
False negative 7 5 2 12
Sensitivity (95% CI) 63% (38-84%) 75% (51-91%) 90% (68-99%) 40% (19-64%)
Specificity (95% CI) 91% (85-94%) 87% (81-91%) 57% (48-65%) 98% (95-100%)
PPV (95% CI) 41% (24-61%) 39% (23-55%) 19% (12-29%) 73% (39-94%)
NPV (95% CI) 96% (92-98%) 97% (93-99%) 98% (93-100%) 94% (89-97%)
PLR (95% CI) 7 (4-12) 6 (4-9) 2 (2-3) 24 (7-83)
NLR (95% CI) 0.4 (0.2-0.7) 0.3 (0.1-0.6) 0.2 (0.1-0.6) 0.6 (0.4-0.9)
OR (95% CI) 16 (6-46) 19 (7-56) 12 (3-.) 39 (10-154)

VIA: visual inspection with acetic acid; DC: digital cervicography; 95% CI: 95% confidence interval; PPV: positive predictive value; NPV: negative predictive value; PLR: positive likelihood ratio; NLR: negative likelihood ratio; OR: odds ratio