Table 4.
Selected GO Biological Processes associated with transcriptionally active genes to which ERα was bound within 25 kB of the transcriptional start site following estrogen treatment of WHSC1L1 knock‐down SUM‐44 cells.
| Category | ID | Name | q‐Value Bonferroni | Hit count in query list | Hit count in genome |
|---|---|---|---|---|---|
| GO: Biological Process | GO:0009888 | Tissue development | 1.27E‐08 | 389 | 1794 |
| GO: Biological Process | GO:1902531 | Regulation of intracellular signal transduction | 3.81E‐08 | 336 | 1518 |
| GO: Biological Process | GO:0060429 | Epithelium development | 3.36E‐05 | 246 | 1110 |
| GO: Biological Process | GO:0012501 | Programmed cell death | 4.54E‐05 | 376 | 1832 |
| GO: Biological Process | GO:0008202 | Steroid metabolic process | 1.40E‐04 | 86 | 304 |
| GO: Biological Process | GO:0051056 | Regulation of small GTPase mediated signal transduction | 2.67E‐04 | 122 | 483 |
| GO: Biological Process | GO:0030855 | Epithelial cell differentiation | 4.68E‐04 | 142 | 589 |
| GO: Biological Process | GO:0048545 | Response to steroid hormone | 6.45E‐04 | 100 | 381 |
| GO: Biological Process | GO:0009725 | Response to hormone | 6.98E‐04 | 195 | 871 |
| GO: Biological Process | GO:0007264 | Small GTPase mediated signal transduction | 7.41E‐04 | 170 | 739 |
| GO: Biological Process | GO:0007265 | Ras protein signal transduction | 9.73E‐04 | 128 | 524 |