Table 3. Unadjusted and Adjusted Associations of Exposure to Violence with Virologic and Immunologic Outcomes Among 268 Youth with PHIV, Pediatric HIV/AIDS Cohort Study (2008-2013).

	HIV RNA>400 copies/mL				CD4%<25%
	OR (95% CI)	p	Adjusted OR (95% CI)	p	OR (95% CI)	p	Adjusted OR (95% CI)	p
Any Youth-reported Violence Exposure, past year (referent: none)	2.70 (1.53, 4.81)	<0.001	1.91 (1.02, 3.55)	0.04	2.18 (1.20, 3.95)	0.01	1.52 (0.79, 2.92)	0.21
Youth Direct Violence Victimization, past year (referent: none)	1.94 (0.82, 4.42)	0.12	1.69 (0.67, 4.24)	0.27	0.81 (0.26, 2.07)	0.68	0.63 (0.21, 1.88)	0.40
Youth Indirect Exposure to Violence, past year (referent: none)	2.75 (1.53, 4.94)	<0.001	1.84 (0.97, 3.48)	0.06	3.07 (1.67, 5.64)	<0.001	2.15 (1.11, 4.17)	0.02
Youth Exposure to Violence score	1.58 (1.18, 2.13)	0.002	1.29 (0.93, 1.78)	0.13	1.42 (1.04, 1.91)	0.02	1.17 (0.83, 1.64)	0.37
Caregiver History of Assault in Adulthood (referent: none)	1.38 (0.76, 2.49)	0.28	1.14 (0.60, 2.17)	0.68	1.09 (0.57, 2.04)	0.78	0.85 (0.43, 1.68)	0.65
Caregiver History of Assault by Partner (referent: none)	1.75 (0.93, 3.24)	0.08	1.36 (0.69, 2.66)	0.37	1.31 (0.66, 2.50)	0.43	0.95 (0.46, 1.94)	0.88
Combined Youth/Caregiver Exposure to Violence score	1.40 (1.12, 1.76)	0.004	1.19 (0.93, 1.52)	0.18	1.21 (0.95, 1.52)	0.12	1.00 (0.77, 1.30)	0.99

Separate models were fit for each type of violence exposure. Adjusted models were adjusted for age, caregiver relationship, caregiver education level and caregiver living with partner/spouse. OR=Odds Ratio; CI=Confidence Interval; PHIV=Perinatally-acquired HIV infection