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Effect of GDNPs 2 on chronic colitis in IL10−/− mice. (A) Spleen/body weight. (B) Colon length. (C) MPO activity. (D) Representative H&E-stained colon sections. Inflammatory cells in the lamina propria are indicated by arrowheads. (E) Pro-inflammatory cytokines mRNAs were quantified by real-time RT-PCR. *p < 0.05, **p < 0.01, ***p < 0.001; ns, not significant. Scale bar = 100 μm. (n=7)
