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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Am J Kidney Dis. 2016 Apr 13;68(1):138–147. doi: 10.1053/j.ajkd.2016.01.030

Figure 4.

Figure 4

Schematic of PLA2R structure, showing the sites of polymorphisms associated with primary membranous nephropathy (represented by black dots) and the location of common epitopes identified in Coenen et al58 (single asterisk) and Svobodova et al33 (double asterisk). Abbreviations and definitions: CysR, cysteine-rich (ricin B) domain; FnII, fibronectin II-like domain; CTLD, C-type lectin-like domains 1–8; M292V, methionine to valine substitution at amino acid 292; H300D, histidine to aspartate substitution at amino acid 300; G1106S, glycine to serine substitution at amino acid 1,106.