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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: J Invest Dermatol. 2016 Mar 25;136(7):1429–1437. doi: 10.1016/j.jid.2016.03.019

Figure 2.

Figure 2

Increased EDC gene expression in WT skin tissue treated with in vitro derived mast cell supernatants. Ear tissues from WT mice were incubated in the presence of mast cell supernatants or mast cell media for 24h. A, Expression of EDC genes in RNA isolated from ear tissue was determined by qPCR analysis. B, Flg expression was assessed in tissue from WT or KitW-sh/W-sh mice incubated in mast cell supernatants as above. C, Flg expression was assessed in tissue from WT mice incubated in mast cell supernatants from WT or Hdc−/− mast cells, or with histamine, as indicated. Data are shown for 3–5 mice per group and representative of 2–4 experiments that yielded similar results. *p < 0.05.

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