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Sagittal view (x = 2) of gray matter volume increases following 1 month of daily morphine. Images of morphine-associated volumetric increases from the current study (blue) and the previous study (yellow) by Younger et al. [13] are overlaid on a 7 T structural image, depicting spatial locations of changes in the pregenual cingulate. Images are thresholded at voxel-level false discovery rate of P < 0.01.
