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Glutamine-glutamate pathway in astrocytes and neurons; Glutathione synthesis in astrocytes and neurons; lactate production from malate in astrocytes. Abbreviations: Glu, Glutamate; Gln, Glutamine; GS, Glutamine Synthetase; PAG, phosphate-activated glutaminase; TCAC, tricarboxylic acid cycle; GSH, gluthation; Cys, Cysteine; Gly, Glycine; GCL, glutamine Cys ligase; GSH-syn, GSH synthetase.
