FIGURE 2.

Parasitaemia and survival rate of BALB/c mice infected with blood-stage P. yoelli 17XNL non-lethal strain and co-infected with Leishmania sp. and P. yoelii 17XNL. (A,C) Malaria parasitaemia in P. yoelii single-infected mice (Py) and in mice co-infected with L. braziliensis/P. yoelii (Lb+Py) (A) or with L. amazonensis/P. yoelii (La+Py) (C). (B,D) Comparison of the survival rate in Py single-infected and Lb+Py co-infected (B) or La+Py co-infected mice (D). Parasitaemia results are expressed by the mean ± SEM of at least 10 mice per group. The Mann–Whitney test was used to compare Py single-infected and co-infected groups. Survival rates were compared by Mantel-Cox test. ^∗p < 0.05 and ^∗∗p < 0.01, respectively. Arrows indicate the time of Leishmania (a) and P. yoelii (b) infection.