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. 2016 Jun 27;7:982. doi: 10.3389/fmicb.2016.00982

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Copyright © 2016 Pinna, Silva-dos-Santos, Perce-da-Silva, Oliveira-Ferreira, Villa-Verde, De Luca and Banic.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Alterations in the thymus relative weight after infection with P. yoelii (Py), L. braziliensis (Lb), L. amazonensis (La), or co-infection with Leishmania sp. and P. yoelii. Thymus relative weight in uninfected controls (open bars) were compared to those obtained in Py single-infected mice (black bars) and in animals co-infected (checkered bars) or single infected (gray bars) with L. braziliensis (A) or L. amazonensis promastigotes (B). Results are expressed by the mean ± SEM of 4–6 mice per group. The Mann–Whitney test was used to compare thymus relative weight between groups. (^∗) statistically different from control, (#) statistically different from Leishmania single infection and (§) statistically different from Leishmania/P. yoelii co-infected group.