Parameter	SEM	βa	t	P
MOTOR EVOKED POTENTIAL (mV)
Conditioned pain modulation (CPM) during CPM/task
No respondera	0.61	0.15	4.09	0.00*
Brazilian Portuguese catastrophizing scale (BP-PCS)	0.007	0.009	0.74	0.46
State-anxiety (STAI-T)	−0.01	0.01	−1.50	0.14
INTRACORTICAL FACILITATION (RATIO: ICF/TEST STIMULUS)
Conditioned pain modulation (CPM) during CPM/task	0.33	0.07	4.50	0.00*
No respondera
Brazilian Portuguese catastrophizing scale (BP-PCS)	0.004	0.004	0.88	0.38
State-anxiety (STAI-T)	0.004	0.006	0.70	0.48
SHORT INTRACORTICAL INHIBITION (RATIO: SICI/TEST STIMULUS)
Conditioned pain modulation (CPM) during CPM/task	−0.02	0.03	−0.62	0.54
No responder a
Brazilian Portuguese catastrophizing scale (BP-PCS)	−0.01	0.02	−0.34	0.80
State-anxiety (STAI-T)	1.85	0.003	0.007	0.99
CORTICAL SILENT PERIOD
Conditioned pain modulation (CPM) during CPM/task	10.82	6.66	1.62	0.11
No respondera
Brazilian Portuguese catastrophizing scale (BP-PCS)	−0.19	0.40	−0.47	0.64
State-anxiety (STAI-T)	−0.47	0.50	−0.94	0.36
BRAZILIAN PROFILE OF CHRONIC PAIN: SCREEN (B-PCP:S)
Conditioned pain modulation (CPM) during CPM/task	7.81	3.13	2.48	0.01*
No respondera
Brazilian Portuguese catastrophizing scale (BP-PCS)	0.80	0.18	4.24	0.00*
State-anxiety (STAI-T)	0.51	0.24	2.17	0.03*
QUANTITATIVE SENSORY TESTING (°C)
Conditioned pain modulation (CPM) during CPM/task	−3.82	1.41	−2.70	0.01*
No respondera
Brazilian Portuguese catastrophizing scale (BP-PCS)	0.08	0.08	0.99	0.33
State-anxiety (STAI-T)	−0.19	0.10	−1.82	0.07
BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) PG/ML (log)
Conditioned pain modulation (CPM) during CPM/task	0.39	0.14	2.66	0.01*
No respondera
Brazilian Portuguese catastrophizing scale (BP-PCS)	−0.05	0.09	−0.61	0.54
State-anxiety (STAI-T)	−0.01	0.01	−1.47	0.15

^aReference category is no responder, hence a positive value mean that the mean was higher in no responder.

CPM-task [no responder (NPS (0–10) HPT1–HPT0 ≥ 0) or responder (NPS (0–10) HPT1–HPT0 < 0]

^*P < 0.05.