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. 2016 May;13(4):282–289. doi: 10.11909/j.issn.1671-5411.2016.04.012

Table 2. Clinical factors related to TEG-MAADP measured after 5-day ticagrelor maintenance treatment in ticagrelor treated ACS patients (n = 176).

Variables β coefficient 95% CI *Adjusted
P value
Age (in decades) 1.13 0.99 to 3.26 0.29
Female gender 2.64 –2.79 to 8.07 0.34
BMI (per 5 kg/m2) 1.11 –3.81 to 15.90 0.65
Current smoking status –1.72 –5.87 to 2.43 0.41
Diabetes mellitus –1.52 –5.37 to 2.32 0.46
Renal dysfunction 9.75 –14.37 to 33.87 0.43
PPI 3.80 –1.85 to 9.45 0.19
Statins –3.19 –14.04 to 7.66 0.56
CCB –4.08 –7.96 to –0.20 0.04
LVEF –0.31 –0.57 to –0.05 0.02
Platelet count 0.02 –0.01 to 0.05 0.29
eGFR (per 30 mL/min per 1.73 m2) 0.05 –0.06 to 0.15 0.38

*Adjusted by the baseline demographic [gender, age (in decades), BMI (per 5 kg/m2), smoking status and comorbidities (diabetes mellitus, renal dysfunction), co-medications (PPI, statins, CCB), laboratory examination [LVEF, platelet count and creatinine-based eGFR (per 30 mL/min per 1.73 m2)]. ACS: acute coronary syndrome; BMI: body mass index; CCB: calcium channel blockers; eGFR: estimates of the glomerular filtrationrate; LVEF: left ventricular ejection; MAADP: ADP-induced platelet-fibrin clot strength; PPI: proton pump inhibitor; TEG: thrombelastography.