Table 1.
Patients' profile
| District(State) | Clinical presentation | Investigations | Imaging diagnosis | Splenic pathology |
|---|---|---|---|---|
| 1. Nagpur (Maharashtra) | 36 y, Male, Pain Lt upper abdomen Splenic infarction, Splenectomy on 10 Aug 99 | Hb 11.6g/dl; TLC 10,600/cmm; DLC P63L32M1E4; Sickling test, Smear, and HB Electrophoresis not done | Splenic infarction | Weight190g, Size 9×5x5cm, Old infarction with vaso-occlusion by aggregates of sickled RBCs. No bacterial/fungal colonies |
| 2. Srikakulum (Andhra Pradesh) | 30 y, Male, Pain Lt upper abdomen at High Altitude; Splenic infarction, Splenectomy on 25 Jul 03 | Hb 12.8g/dl; TLC 11,400/cmm; DLC P73L21M1E5; Sickling test, Smear, and HB Electrophoresis not done | Splenic infarction | Wt 390g, Size10×9x6cm, Recent haemorrhagic infarction with vaso-occlusion by sickled RBCs No bacterial/fungal colonies |
| 3. Bargar(West Bengal) | 23 y, Male, Pain Lt upper abdomen, fever, Splenic Abscess; Splenectomy on 14 Nov 03 | Hb 14.8g/dl; TLC 7,300/cmm; DLC P61L34M2E3; Sickling test, Smear, and HB Electrophoresis not done | Splenic Abscess | Wt 150g, Size 6.5×5x5cm, Hematoma on cut surface 4×3.5cm Old infarction with fibrosis &vasoocclusion by sickled RBCs. No bacterial /fungal colonies |
| 4. Visakapatnam (Andhra Pradesh) | 44 y, Male, Pain Lt upper abdomen, fever, Splenic abscess, Splenectomy on 09 Jul 05 | Hb 12.4g/dl; TLC 9,300/cmm; DLC P58L36M2E4; Smear-No abnormality Sickling test Positive HB Electrophoresis A2- 1.9%; S- 41.6%; F- 1.0%; A- 55.5% | Splenic abscess/hematoma | Wt 160g, Size 8×6x3cm, Hematoma, recent haemorrhagic infarction vasoocclusion by sickledRBC No bacterial/fungal colonies |
| 5. Yawatmal(Maharashtra) | 27 y, Male, Pain Lt upper abdomen, fever, Splenic abscess Splenectomy on 15 Sep 05 | Hb 11.2g/dl; TLC 8,900/cmm; DLC P58L36M2E4; Smear No abnormality Sickling test Positive HB Electrophoresis A2- 3.2%; S- 44.1%; F- 0.3%; A- 52.4% | Splenic abscess with splenomegaly | Wt 250g, Size 9×8.5×2.3cm and 2.5×2x1cm, recent haemorrhagic & old fibrotic infarction, vasoocclusionbysickledRBCs No bacterial/fungal colonies |
| 6. Srikakulum (Andhra Pradesh) | 23 y, Male, Pain Lt upper abdomen, low grade fever, Tender Spleenomegaly, Icterus, Pleural effusion, Splenic hematoma / abscess, Splenectomy on 11 Jul 06 | Hb 13.3g/dl; TLC 9,700/cmm; DLC P69L26M2E3; Smear No abnormality Sickling test Positive HB Electrophoresis A2- 1.2%; S- 39.4%; F- 0.5%; A- 58.9% | Splenic pseudocyst | Wt 170g (without hematoma), Size 14×6x1cm and 9×6x3cm Subcapsular & parenchymal hematoma, haemorrhagic infarction vaso-occlusion by sickled RBCs, No bacterial/fungal colonies |
| 7. Akola(Maharashtra) | 33 y, Male, Pain Lt Abdomen at high altitude, no fever, Sub capsular hematoma, Managed conservatively; 29 Jun 05 | Hb 11.1g/dl; TLC 6,800/cmm; DLC P74L18M2E6; Smear No abnormality Sickling test Positive HB Electrophoresis A2- 2.7%; S- 39.5%; F- 0.3%; A- 57.5% | Sub capsular hematoma | NA |
| 8. Katni(Madhya Pradesh) | 42 y, Male, Pain Lt Abdomen, fever, Splenic abscess with pleural effusion, Splenectomy on 08 Aug 06 | Hb 11.4g/dl; TLC 10,400/cmm; DLC P73L17M2E8; Smear No abnormalitySickling test Positive HB Electrophoresis A2- 2.3%; S- 40.8%; F- 0.9%; A- 56% | Sub capsular hematoma | Wt 475g, Size 13×10×5 hematoma, Recent haemorrhagic infarction vaso-occlusion by sickled RBCs, No bacterial/fungal colonies |