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. 2011 Jul 21;64(3):261–262. doi: 10.1016/S0377-1237(08)80110-4

Table 1.

Plasma concentrations of various intravenous anaesthetic agents for specific clinical effects

Drug Skin incision Major surgery Analgesia/sedation
Propofol (μg/ml) 2-6 2.5-7.5 1-3
Midazolam (ng/ml) 150-300 40-100
Methohexital (μg/ml) 5-10 5-15 2-5
Etomidate (ng/ml) 400-600 500-1000 100-300
Sufentanil (μg/ml) 1-3 2-5 0.1-0.2
Alfentanil (μg/ml) 200-300 250-450 50-100
Remifentanil (μg/ml) 4-8 4-8 1-2