Table 1.
Plasma concentrations of various intravenous anaesthetic agents for specific clinical effects
Drug | Skin incision | Major surgery | Analgesia/sedation |
---|---|---|---|
Propofol (μg/ml) | 2-6 | 2.5-7.5 | 1-3 |
Midazolam (ng/ml) | − | 150-300 | 40-100 |
Methohexital (μg/ml) | 5-10 | 5-15 | 2-5 |
Etomidate (ng/ml) | 400-600 | 500-1000 | 100-300 |
Sufentanil (μg/ml) | 1-3 | 2-5 | 0.1-0.2 |
Alfentanil (μg/ml) | 200-300 | 250-450 | 50-100 |
Remifentanil (μg/ml) | 4-8 | 4-8 | 1-2 |