Table 3.
Frequency of T and NK (CD56dim and CD56bright) cells from subjects in different groups.
| Median | Mean ± SD | p value (Kruskal-Wallis test) | |||||
|---|---|---|---|---|---|---|---|
| Healthy | HIV/AIDS | HIV/AIDSWC | Healthy | HIV/AIDS | HIV/AIDSWC | ||
| Percentage (%) | |||||||
| Total lymphocytes | 35.50 | 35.50 | 30.00 | 33.61 ± 9.09 | 35.44 ± 10.44 | 32.39 ± 11.94 | 0.3617 |
| T cells | 55.20 | 59.40 | 57.70 | 54.48 ± 11.54 | 60.70 ± 9.14 | 57.52 ± 11.28 | 0.2204 |
| CD4 T cells | 53.00 | 38.20a | 23.60ab | 54.44 ± 11.12 | 37.91 ± 10.74 | 26.28 ± 14.99 | <0.0001 |
| CD8 T cells | 36.10 | 53.00a | 62.00a | 35.26 ± 9.96 | 53.12 ± 10.32 | 60.66 ± 15.45 | <0.0001 |
| NK cells | 11.30 | 9.70 | 11.60 | 13.21 ± 6.69 | 11.15 ± 7.08 | 12.93 ± 6.75 | 0.4699 |
| CD56dim NK subset | 96.50 | 95.70 | 94.80 | 95.72 ± 2.94 | 94.23 ± 5.10 | 93.70 ± 5.14 | 0.2499 |
| CD56bright NK subset | 3.70 | 4.50 | 5.10 | 4.41 ± 2.99 | 5.26 ± 4.14 | 6.37 ± 5.60 | 0.3283 |
|
| |||||||
| Absolute numbers (cells/mm3) | |||||||
| WBC count | 7000 | 5500 | 6800 | 7148.00 ± 2233.85 | 5924.00 ± 1860.17 | 7261.90 ± 2789.52 | 0.0722 |
| Total lymphocytes | 2280 | 1960 | 2110 | 2256.40 ± 566.09 | 2007.60 ± 597.02 | 2341.42 ± 1152.39 | 0.4601 |
| T cells | 1159 | 1198 | 1314 | 1214.16 ± 416.83 | 1229.88 ± 454.55 | 1329.95 ± 640.95 | 0.8751 |
| CD4 T cells | 655 | 453a | 280ab | 665.36 ± 272.59 | 472.56 ± 228.92 | 355.42 ± 303.63 | 0.0002 |
| CD8 T cells | 369 | 603a | 753a | 430.08 ± 209.90 | 645.84 ± 252.61 | 812.38 ± 437.61 | 0.0007 |
| NK cells | 274 | 194 | 248 | 292.20 ± 173.04 | 211.76 ± 131.60 | 310.28 ± 235.15 | 0.1501 |
| CD56dim NK subset | 257 | 185 | 239 | 281.60 ± 172.52 | 203.32 ± 131.54 | 294.76 ± 226.17 | 0.1817 |
| CD56bright NK subset | 9 | 7 | 10 | 10.92 ± 7.29 | 7.72 ± 4.92 | 15.23 ± 12.39 | 0.1137 |
Percentage values represent the frequency (in percentage and absolute numbers) in median of T cells, CD4+ T cells, CD8+ T cells, and NK cells among all peripheral blood lymphocytes and the frequency of CD56dim and CD56bright NK cells among the NK cell population. Means and standard deviations (SD) are also shown. Significant p values are highlighted in boldface type. a = statistical difference to the healthy group (p < 0.05); b = statistical difference to the HIV/AIDS group (p < 0.05). Statistical comparisons made by Kruskal-Wallis (with Student-Newman-Keuls posttest).