Table 5.
Correlation analysis between NCRs and CD4 T cells, CD4/CD8 ratio, and days since HIV/AIDS diagnosis.
| NKp30 | CD4 T cells | CD4/CD8 ratio | Days since HIV/AIDS diagnosis | |
|---|---|---|---|---|
| NK cells | ||||
| Healthy donors | ||||
| NKp46 | 0.7272 (p < 0.0001) | 0.2585 (p = 0.2121) | −0.1408 (p = 0.5019) | NA |
| NKp30 | — | 0.1617 (p = 0.4400) | −0.0004 (p = 0.9985) | NA |
| HIV/AIDS group | ||||
| NKp46 | 0.9046 (p < 0.0001) | 0.2400 (p = 0.2477) | 0.1928 (p = 0.3559) | 0.0677 (p = 0.7478) |
| NKp30 | — | 0.2821 (p = 0.1718) | 0.3249 (p = 0.1130) | 0.1428 (p = 0.4960) |
| HIV/AIDSWC group | ||||
| NKp46 | 0.7580 (p < 0.0001) | 0.3351 (p = 0.1375) | 0.0754 (p = 0.7454) | 0.0948 (p = 0.6827) |
| NKp30 | — | 0.3677 (p = 0.1010) | 0.2671 (p = 0.2417) | 0.3910 (p = 0.0795) |
|
| ||||
| CD56dim NK subset | ||||
| Healthy donors | ||||
| NKp46 | 0.7838 (p < 0.0001) | 0.2220 (p = 0.2861) | −0.1461 (p = 0.4859) | NA |
| NKp30 | — | 0.2208 (p = 0.2889) | 0.0192 (p = 0.9273) | NA |
| HIV/AIDS group | ||||
| NKp46 | 0.9297 (p < 0.0001) | 0.2213 (p = 0.2877) | 0.1986 (p = 0.3412) | 0.0962 (p = 0.6473) |
| NKp30 | — | 0.3037 (p = 0.1399) | 0.3446 (p = 0.0916) | 0.1946 (p = 0.3512) |
| HIV/AIDSWC group | ||||
| NKp46 | 0.7156 (p = 0.0003) | 0.3558 (p = 0.1133) | 0.0864 (p = 0.7095) | 0.1039 (p = 0.6540) |
| NKp30 | — | 0.3571 (p = 0.1119) | 0.3112 (p = 0.1696) | 0.4727 (p = 0.0504) |
|
| ||||
| CD56bright NK subset | ||||
| Healthy donors | ||||
| NKp46 | 0.7121 (p < 0.0001) | 0.6241 (p = 0.0008) | 0.0698 (p = 0.7402) | NA |
| NKp30 | — | 0.6232 (p = 0.0009) | 0.2029 (p = 0.3307) | NA |
| HIV/AIDS group | ||||
| NKp46 | 0.3303 (p = 0.1068) | 0.3947 (p = 0.0508) | 0.0571 (p = 0.7863) | 0.2101 (p = 0.3135) |
| NKp30 | — | 0.0987 (p = 0.6386) | 0.1911 (p = 0.3600) | 0.3172 (p = 0.1222) |
| HIV/AIDSWC group | ||||
| NKp46 | 0.8096 (p < 0.0001) | 0.3094 (p = 0.1722) | −0.0091 (p = 0.9687) | −0.1055 (p = 0.6489) |
| NKp30 | — | 0.2354 (p = 0.3043) | 0.0524 (p = 0.8215) | 0.0975 (p = 0.6743) |
The numbers are shown as “rs (p)”. p < 0.05. Significant p values are highlighted in bold. The correlation coefficient rs > 0 shows positive correlation; rs < 0 stands for negative correlation. p < 0.05 and rs > 0.4 indicates the significant correlation between the two indexes. NA: not applicable.