Fig. 4. HMME-PDT induced changes in caspase 3, 9 and Cyto C in canine breast cancer cells. (A) HMME-PDT induced the release of Cyto C at 6, 12, 24, and 48 h after PDT. (B and C) The activities of caspase-9 and caspase-3 were remarkably stimulated from 6 h and 12 h, respectively, when compared with the mock treated cells (n = 3, mean ± SD).
