Table 2.
Treatment strategy for renal protection
| Intervention | Therapeutic goal |
|---|---|
| Angiotensin converting enzyme inhibitor or Angiotensin receptor blocker (consider combination if goal not achieved with monotherapy) | Proteinuria less than 0.5 gms/day GFR decline less than 2ml/mt/yr |
| Dietary protein restriction | 0.6-0.8 gms/kg/day |
| Additional antihypertensive therapy | BP <130/80 mm of Hg |
| Dietary salt restriction (in presence of hypertension) | 3-5 gms/day |
| Tight glycemic control | Hb A1c <6.5% |
| Reduce elevated calcium phosphate product | Normal values |
| Lipid lowering therapy | LDL-C less than 100 mgm/dl |
| Anti platelet therapy | Thrombosis prophylaxis |
| Correction of anaemia | Hb more > 12 gms% |
| Smoking cessation | Abstinence |
| Weight control | Ideal body weight |
| Prevent urinary tract infection as in reflux nephropathy |