Table 4.
Data representing mean ± SD of separate experiments for attachment assay of CFT073 wt, CFT073 Δdam mutant, cC119, and cC119 Δdam mutant to HEK-293 kidney and HTB-9 bladder cells.
| E. coli strain | Colony count |
|||||
|---|---|---|---|---|---|---|
| HEK-293 | HTB-9 | |||||
| Mean CFU/ml (×104) | Mean CFU/ml (×105) | Mean CFU/ml (×105) | Mean CFU/ml (×106) | |||
| Adherent | Total | % Adherent | Adherent | Total | % Adherent | |
| CFT073 wt | 1.55 ± 0.35 | 3.02 ± 2.51 | 5.1 | 3.02 ± 2.51 | 11.6 ± 6.58 | 2.6 |
| CFT073 Δdam | 0.55 ± 0.05 | 3.04 ± 2.91 | 1.8 | 3.04 ± 2.91 | 3.97 ± 0.73 | 7.7 |
| cC119 | 5.20 ± 0.10 | 11.9 ± 7.73 | 4.4 | 11.9 ± 7.73 | 52.2 ± 18.27 | 2.3 |
| cC119 Δdam | 1.70 ± 0 | 4.10 ± 2.95 | 4.1 | 4.10 ± 2.95 | 15.3 ± 10.01 | 2.7 |